BCMP 236

Instructors: Buhrlage, Dubreuil

This course will discuss principles of drug discovery drug modalities and drug pharmacology.  In the first part of the course, fundamental aspects of receptor and enzyme targeting agents, drug mechanism, drug metabolism, pharmacokinetics and pharmacodynamics, small molecules, proteins, and nucleic acid drugs will be described. In the second part of the course, pharmacology of therapeutics that act on the cardiovascular, immunologic, and central nervous systems will be covered. The course will include frontier lectures on antiviral agents, cardiac drugs, and treatments for brain diseases and a journal club on specialized topics in drug discovery.  A range of knowledgeable instructors enlisted from the Harvard Medical School faculty and pharmaceutical scientists will participate in teaching this course.